COLEC12
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB25253
unconjugated
Applikationshinweise
IHC/IF (M,R) 1:500-1:1500/1:500-1:1300
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Target
COLEC12
(Collectin Sub-Family Member 12 (COLEC12))
Andere Bezeichnung
Colec12
Hintergrund
This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells.