CD3 Antikörper
Kurzübersicht für CD3 Antikörper (ABIN7073386)
Target
Alle CD3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse CD3
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Applikationshinweise
- WB (H,M,R) 1:500-1:1000, IHC/IF (H,M,R) 1:250-1:1000/1:250-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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: "The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis." in: Theranostics, Vol. 11, Issue 19, pp. 9503-9518, (2022) (PubMed).
: "Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations." in: Oncogene, Vol. 40, Issue 2, pp. 355-368, (2021) (PubMed).
: "Optimization Strategy for Generating Gene-edited Tibet Minipigs by Synchronized Oestrus and Cytoplasmic Microinjection." in: International journal of biological sciences, Vol. 15, Issue 12, pp. 2719-2732, (2020) (PubMed).
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: "The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis." in: Theranostics, Vol. 11, Issue 19, pp. 9503-9518, (2022) (PubMed).
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- CD3
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Andere Bezeichnung
- CD3
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Hintergrund
- The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development.
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Molekulargewicht
- 21 kDa
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Gen-ID
- 12501
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NCBI Accession
- NP_031674
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UniProt
- P22646
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Pathways
- T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway
Target
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