WTX Antikörper
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- Target Alle WTX (AMER1) Antikörper anzeigen
- WTX (AMER1) (APC Membrane Recruitment Protein 1 (AMER1))
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser WTX Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Human, Ratte
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse FAM123B
- Top Product
- Discover our top product AMER1 Primärantikörper
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anti-APC Membrane Recruitment Protein 1 (AMER1) (AA 681-708) antibody
AMER1 Reaktivität: Human, Maus WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB18795 unconjugated
anti-APC Membrane Recruitment Protein 1 (AMER1) antibodyAMER1 Reaktivität: Human, Maus ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-APC Membrane Recruitment Protein 1 (AMER1) antibodyAMER1 Reaktivität: Human, Maus IHC, WB, FACS Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB (H,M,R) 1: 500-1: 1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- WTX (AMER1) (APC Membrane Recruitment Protein 1 (AMER1))
- Andere Bezeichnung
- FAM123B (AMER1 Produkte)
- Synonyme
- 2810002O09Rik antikoerper, AW492303 antikoerper, Fam123b antikoerper, Wtx antikoerper, FAM123B antikoerper, OSCS antikoerper, WTX antikoerper, RGD1560322 antikoerper, fam123b antikoerper, APC membrane recruitment 1 antikoerper, APC membrane recruitment protein 1 antikoerper, Amer1 antikoerper, AMER1 antikoerper, amer1 antikoerper
- Hintergrund
- Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex. Acts both as a positive and negative regulator of the Wnt signaling pathway, depending on the context: acts as a positive regulator by promoting LRP6 phosphorylation. Also acts as a negative regulator by acting as a scaffold protein for the beta-catenin destruction complex and promoting stabilization of Axin at the cell membrane. Promotes CTNNB1 ubiquitination and degradation. Involved in kidney development.
- Molekulargewicht
- 125 kDa
- Gen-ID
- 72345
- NCBI Accession
- NP_780388
- UniProt
- Q7TS75
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