alpha Actinin Antikörper
Kurzübersicht für alpha Actinin Antikörper (ABIN7073023)
Target
Alle alpha Actinin (ACTN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Maus, Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Human ACTN1
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Applikationshinweise
- WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:500-1:1000/1:500-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))
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Andere Bezeichnung
- alpha Actinin
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Hintergrund
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.
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Molekulargewicht
- 103 kDa
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Gen-ID
- 109711
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NCBI Accession
- NP_001093
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UniProt
- P12814
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Pathways
- Cell-Cell Junction Organization, Negative Regulation of Transporter Activity
Target
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