Rekombinanter CCR9 Antikörper (N-Term)

Produktnummer ABIN7072662

Dieses Anti-CCR9-Antikörper ist ein Kaninchen Chimeric-Antikörper zur Detektion von CCR9 in FACS und Neut. Geeignet für Maus.

Kurzübersicht für Rekombinanter CCR9 Antikörper (N-Term) (ABIN7072662)

Target: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CCR9 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Neutralization (Neut)

Klon: 9B1

Produktdetails anti-CCR9 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Anti-CCR9 [9B1], Rabbit IgG, kappa

Spezifität: 9B1 antibody recognizes CCR9 at the N-terminus. CCR9 is a member of the G protein coupled receptor family and is involved in T cell development in the thymus and in gut-associated immune response. Mouse CCR9 is highly expressed on different stages of thymocytes and upregulated on CD4+CD8+ cells.

Produktmerkmale:

Original Species of Ab: Rat

Original Format of Ab: IgG2a

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by immunizing rats with KLH-conjugated linear peptide corresponding to the N-terminus of mouse CCR9.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody is recommended for the detection and analysis of CCR9 via flow cytometry (Farazuddin et al., 2019). Furthermore, it was demonstrated that this 9B1 antibody was capable of neutralizing CCR9 function, as it inhibited CCL25-induced calcium mobilization in L1.2-CCR9 cells (Rivera-Nieves et al., 2006).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CCR9

Target: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Andere Bezeichnung: CCR9

Hintergrund: CD199, C-C chemokine receptor type 9, C-C CKR-9, CC-CKR-9, CCR-9, G-protein coupled receptor 28, GPR-9-6, CDw199, 9B-1

UniProt: Q9WUT7