Rekombinanter VCAM1 Antikörper

Produktnummer ABIN7072646

Der Kaninchen Chimeric Anti-VCAM1-Antikörper wurde für FACS und BP validiert. Er ist geeignet, VCAM1 in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter VCAM1 Antikörper (ABIN7072646)

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser VCAM1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Blocking Peptide (BP)

Klon: B-K9 (C106-K9)

Produktdetails anti-VCAM1 Antikörper

Verwendungszweck: Anti-CD106 [B-K9 (C106-K9)], Rabbit IgG, kappa

Spezifität: B-K9 antibody recognizes CD106 (VCAM1). CD106 is a member of the Ig superfamily. It is a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by immunizing Balb/c mice against activated human umbilical vein endothelial cells (HUVEC).

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: B-K9 antibody inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells, and thus it blocks the ability of white blood cells to attach themselves to the activated epithelium during, for instance, inflammation. Consequently, this antibody might be used in research where leukocytes adhesion-blocking is required (Uotila et al., 2014, Wagner et al. 2011).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu VCAM1

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Andere Bezeichnung: CD106

Hintergrund: VCAM1, Vascular cell adhesion protein 1, V-CAM 1, INCAM-100

UniProt: P19320

Pathways: Carbohydrate Homeostasis