Rekombinanter CD53 Antikörper

Produktnummer ABIN7072633

Dieses Kaninchen Chimeric-Antikörper erkennt spezifisch CD53 in FACS, IF und Func. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter CD53 Antikörper (ABIN7072633)

Target: CD53

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CD53 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Klon: 161-2

Produktdetails anti-CD53 Antikörper

Verwendungszweck: Anti-CD53 [161-2 (53/2)], Rabbit IgG, kappa

Spezifität: This antibody recognizes human CD53. It does not react with the baboon and horse antigen. Cd53 is a member of tetraspanin family and is involved in cellular activation as part of a signal transduction complex involving other membrane glycoproteins.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by immunizng mice with stimulated human leukocytes.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody is recommended for the detection and analysis of CD53 via flow cytometry and immunofluorescence. Additionally, one group utilized this antibody for the ligation of the CD53 antigen while researching the potential involvement of tetraspanins (such as CD53) in tumor metastasis (Yunta et al., 2002). Furthermore, CD53 appears to be the marker with widest reactivity as well as the marker with the strictest specificity to hematopoietic cells, as it is expressed on monocytes and macrophages, dendritic cells, osteoblasts and osteoclasts, and on T and B cells from every stage of differentiation but is absent from platelets, red blood cells.

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CD53

Target: CD53

Andere Bezeichnung: CD53

Hintergrund: Tetraspanin-25, Leukocyte surface antigen CD53, Cell surface glycoprotein CD53, Tspan-25

UniProt: P19397