Rekombinanter Transferrin Receptor Antikörper

Produktnummer ABIN7072542

Dieses Anti-Transferrin Receptor-Antikörper ist ein Kaninchen Chimeric-Antikörper zur Detektion von Transferrin Receptor in FACS und Dep. Geeignet für Maus.

Kurzübersicht für Rekombinanter Transferrin Receptor Antikörper (ABIN7072542)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser Transferrin Receptor Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Depletion (Dep)

Klon: R17 217-1-3

Produktdetails anti-Transferrin Receptor Antikörper

Verwendungszweck: Anti-Transferrin receptor [R17 217.1.3], Rabbit IgG, kappa

Spezifität: The transferrin receptor is necessary for cellular iron uptake by the process of receptor-mediated endocytosis. Mice that are deficient in this receptor show impaired erythroid development and abnormal iron homeostasis.

Produktmerkmale:

Original Species of Ab: Rat

Original Format of Ab: IgG2a

Aufreinigung: Protein A affinity purified

Immunogen: The antibody was obtained from a fusion of the murine myeloma S 194/5.XXO.BU. 1 with spleen cells from a BDIX rat immunized with the Friend erythroleukemia 745.6.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: R17 217.1.3 was used in conjunction with flow cytometry to identify murine hematopoietic progenitor cells expressing the transferrin receptor (Lesley et al, 1984). Injection of mice with R17 217.1.3 results in CD71+ erythroid splenocyte cell depletion (Torow et al, 2015).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: Transferrin receptor

Hintergrund: CD71, Transferrin receptor protein 1, TR, , TfR1, Trfr

Pathways: Transition Metal Ion Homeostasis