Rekombinanter CD276 Antikörper (Extracellular Domain)
Kurzübersicht für Rekombinanter CD276 Antikörper (Extracellular Domain) (ABIN7072434)
Target
Alle CD276 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-242, Extracellular Domain
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Verwendungszweck
- Anti-B7-H3 [MJ18], Rabbit IgG, kappa
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Spezifität
- This antibody binds to mouse B7-H3 and does not react with other B7-family molecules.
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Produktmerkmale
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Original Species of Ab: Rat
Original Format of Ab: IgG1
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Aufreinigung
- Protein A affinity purified
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Immunogen
- This antibody was generated by immunizing Sprague Dawley rats with B7-H3-Ig, consisting of the extracellular domain (aa1-242 of mouse B7-H3) linked to the Fc portion of mouse IgG2a, emulsified in CFA (Difco). The antibody was selected by its reactivity to mouse B7-H3-transfected cells, but not to parental cells by flow cytometry.
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Isotyp
- IgG kappa
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anti-CD276 (CD276) (AA 47-219) antibody
CD276 Reaktivität: Human WB, FACS, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD276 (CD276) (AA 29-466) antibodyCD276 Reaktivität: Human ELISA, FACS, IHC, ICC Wirt: Maus Monoclonal 8C1C2 unconjugated
anti-CD276 (CD276) (AA 493-522), (C-Term) antibodyCD276 Reaktivität: Human WB, FACS, IHC (p), IF Wirt: Kaninchen Polyclonal RB31111 unconjugated
anti-CD276 (CD276) (AA 47-213) antibodyCD276 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD276 (CD276) (AA 100-200) antibodyCD276 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD276 (CD276) (AA 237-358) antibodyCD276 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4E12 unconjugated
anti-CD276 (CD276) (AA 47-219) antibodyCD276 Reaktivität: Human WB Wirt: Maus Monoclonal C9 unconjugated
anti-CD276 (CD276) (AA 29-200) antibodyCD276 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD276 (CD276) (AA 101-200) antibodyCD276 Reaktivität: Human, Maus WB, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-CD276 (CD276) (AA 29-245) antibodyCD276 Reaktivität: Human ELISA, FACS Wirt: Kaninchen Monoclonal DM53 unconjugated Recombinant Antibody
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Applikationshinweise
- This antibody has been used to detect murine B7-H3 by flow cytometry. It blocks B7-H3 signalling and can supress priming of Th2-responses and thereby the development of asthmatic responses in an ovalbumin-induced asthma model in BALB/c mice.
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Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD276
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Andere Bezeichnung
- B7-H3
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Hintergrund
- CD276, B7H3
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UniProt
- Q8VE98
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Pathways
- Cancer Immune Checkpoints
Target
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