Rekombinanter CD27 Antikörper

Produktnummer ABIN7072375

Dieses Kaninchen Chimeric-Antikörper erkennt spezifisch CD27 in FACS, IF, IP und Act. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Rekombinanter CD27 Antikörper (ABIN7072375)

Target: CD27 (CD27 Molecule (CD27))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CD27 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Activation (Act)

Klon: LG-3A10

Produktdetails anti-CD27 Antikörper

Verwendungszweck: Anti-CD27 [LG.3A10], Rabbit IgG, kappa

Spezifität: This antibody is specific for mouse CD27, which, as in the human system, is largely restricted to cells of the T cell lineage, and is expressed on the great majority of both αβ and γδ T lymphocytes, and thymocytes.

Kreuzreaktivität: Human, Ratte

Produktmerkmale:

Original Species of Ab: Hamster, Armenian

Original Format of Ab: IgG

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was produced by injecting Armenian hamsters intraperitoneally with a mixture of two murine CD27 tag-expressing Armenian hamster fibroblast clones (AR0524 and AR0530) in Freund's adjuvant

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody is specific for murine CD27, and has been used to assess the distribution of CD27 expression using IF, FC and IP analysis (Gravstein, 1995). Upon cross-linking, this antibody has been shown to induce a 4-fold increase in T cell proliferation in response to suboptimal stimulation with concanavalin A (Gravestein, 1995), indicating that this antibody is able to mimic ligand binding.

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Hamster IgG format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CD27

Target: CD27 (CD27 Molecule (CD27))

Andere Bezeichnung: CD27

Hintergrund: TNFRS7, CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7

UniProt: P41272

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints