Rekombinanter ErbB2/Her2 Antikörper
Kurzübersicht für Rekombinanter ErbB2/Her2 Antikörper (ABIN7072299)
Target
Alle ErbB2/Her2 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-HER2/neu [SER4], Mouse IgG1, kappa
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Spezifität
- The antibody binds specifically to the extracellular domain of human ErbB-2.
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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Aufreinigung
- Protein A affinity purified
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Immunogen
- Recombinant HER2/neu.
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Isotyp
- IgG1 kappa
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Applikationshinweise
- The antibody binds to human ErbB-2, a receptor tyrosine kinase (RTK) controlling cell growth and microtubule stabilization. Full-length antibody or Fab fragments cross-linked by secondary antibody had a growth-inhibiting effect onf ErbB-2 positive MDA-MB-453 cells. This effect was not seen with Fab fragments alone.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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Andere Bezeichnung
- HER2/neu
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Hintergrund
- ERBB2, Receptor tyrosine-protein kinase erbB-2, human epidermal growth factor receptor 2,
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UniProt
- P04626
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development
Target
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