Rekombinanter MMP14 Antikörper (AA 218-233)
Kurzübersicht für Rekombinanter MMP14 Antikörper (AA 218-233) (ABIN7072294)
Target
Alle MMP14 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 218-233
-
Verwendungszweck
- Anti-Membrane type 1 metalloprotease [LEM-2/15], Mouse IgG1, kappa
-
Spezifität
- This antibody binds to residues 218-233 of the V-B loop of MT1-MMP with a Kd of 2.32E10-9M.
-
Produktmerkmale
-
Original Species of Ab: Mouse
Original Format of Ab: IgG1
-
Aufreinigung
- Protein A affinity purified
-
Immunogen
- The cyclic peptide possessing the sequence of residues 218-233 of the V-B-loop of MT1-MMP.
-
Isotyp
- IgG1 kappa
-
-
-
-
Applikationshinweise
- This antibody binds to residues 218-233 of the V-B loop of MT1-MMP which is a mediator of cell migration and is frequently involved in malignancy of tumours by promoting metastasis. The antibody acts as a non-competitive inhibitor of the receptor.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % Proclin 300.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
-
- MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
-
Andere Bezeichnung
- Membrane type 1 metalloprotease
-
Hintergrund
- MT1-MMP
-
Pathways
- Autophagie
Target
-