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STOML2 Antikörper (Intracellular)

STOML2 Reaktivität: Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7043779
  • Target Alle STOML2 Antikörper anzeigen
    STOML2 (Stomatin (EPB72)-Like 2 (STOML2))
    Bindungsspezifität
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 208-222, Intracellular
    Reaktivität
    • 42
    • 22
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 37
    • 5
    • 1
    Kaninchen
    Klonalität
    • 39
    • 4
    Polyklonal
    Konjugat
    • 24
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser STOML2 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 13
    • 13
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    A Rabbit Polyclonal Antibody to Stomatin-like Protein 2
    Spezifität
    Intracellular
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Mouse,human - identical
    Produktmerkmale
    Anti-STOML2/SLP-2 Antibody (ABIN7043779, ABIN7044518 and ABIN7044519)) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot analysis. It has been designed to recognize Stomatin-like protein 2 from human, rat, and mouse samples.
    Aufreinigung
    Affinity purified on immobilized antigen.
    Immunogen

    Immunogen: Synthetic peptide

    Immunogen Sequence: (C)EGTRESAINVAEGKK, corresponding to amino acid residues 208-222 of rat Stomatin-like protein 2

    Isotyp
    IgG
    Top Product
    Discover our top product STOML2 Primärantikörper
  • Applikationshinweise

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

    Application Dilutions Western blot wb: 1:400-1:800

    Kommentare

    Negative Control: BLP-IP002

    Blocking Peptide: BLP-IP002

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • Target
    STOML2 (Stomatin (EPB72)-Like 2 (STOML2))
    Andere Bezeichnung
    STOML2 (STOML2 Produkte)
    Hintergrund
    Paraprotein target 7, EPB72-like protein 2, Stomatin-like protein 2,Stomatin-like protein 2 (STOML2, SLP-2) is a key protein on the mitochondrial inner membrane and a member of the stomatin superfamily. STOML2 is widely expressed in human tissues such as the brain, lung, and kidneys and interacts with prohibitin-1 and 2. It plays an important role in numerous physiological processes including organizing sphingolipid and cholesterol-rich lipid rafts, regulating ion channel conductance, and linking other integral membrane proteins to the peripheral cytoskeleton1,2.STOML2 shares a consensus stomatin signature sequence that defines the stomatin gene family. However, it lacks a NH2-terminal hydrophobic domain shared by other members3.Studies show that STOML2 expression is upregulated in various human cancer tissues including gastric cancer, endometrial adenocarcinoma, and breast cancer. The protein may play an important role in the incidence and development of tumor and it is suggested that SLP-2 is a potential oncogene. Knockdown of STOML2 protein significantly restrains the viability, migration, and invasion of hepatoma cell line1,2.

    Alternative names: STOML2/SLP-2, Paraprotein target 7, EPB72-like protein 2, Stomatin-like protein 2
    Gen-ID
    298203
    NCBI Accession
    NM_013442
    UniProt
    Q4FZT0
    Pathways
    SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
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