GM-CSF Antikörper (AA 65-144)

Produktnummer ABIN704156

Der Kaninchen Polyklonal Anti-GM-CSF-Antikörper wurde für WB, ELISA, IF, IHC (fro) und IHC (p) validiert. Er ist geeignet, GM-CSF in Proben von Human zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für GM-CSF Antikörper (AA 65-144) (ABIN704156)

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GM-CSF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GM-CSF Antikörper

Bindungsspezifität: AA 65-144

Homologie: Human,Mouse,Rat,Dog,Cow,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GM-CSF

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF()

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-GM-CSF Antikörper (ABIN704156)

Anzai, Choi, He, Fenn, Nairz, Rattik, McAlpine, Mindur, Chan, Iwamoto, Tricot, Wojtkiewicz, Weissleder, Libby, Nahrendorf, Stone, Becher, Swirski: "The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes." in: The Journal of experimental medicine, Vol. 214, Issue 11, pp. 3293-3310, (2017) (PubMed).

Hilgendorf, Theurl, Gerhardt, Robbins, Weber, Gonen, Iwamoto, Degousee, Holderried, Winter, Zirlik, Lin, Sukhova, Butany, Rubin, Witztum, Libby, Nahrendorf, Weissleder, Swirski: "Innate response activator B cells aggravate atherosclerosis by stimulating T helper-1 adaptive immunity." in: Circulation, Vol. 129, Issue 16, pp. 1677-87, (2014) (PubMed).

Xue, Chen, Cui, Cao, Zhou, Zheng, Gong: "Expression of hGM-CSF in silk glands of transgenic silkworms using gene targeting vector." in: Transgenic research, Vol. 21, Issue 1, pp. 101-11, (2012) (PubMed).

Details zu GM-CSF

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Andere Bezeichnung: Gm-Csf

Hintergrund:

Synonyms: Granulocyte-Macrophage Colony Stimulating Factor, Burst Promoting Activity, CMCSF, Colony Stimulating Factor 2, Colony stimulating factor, CSF 2, CSF Alpha, CSF, CSF2, Eosinophil Colony Stimulating Factor, GMCSF, Granulocyte Macrophage Colony Stimulating Factor, MGC131935, MGC138897, Molgramostin, Pluripoietin Alpha, Sargramostim, granulocyte-macrophage colony-stimulating factor precursor, CSF2_HUMAN.

Background: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

Gen-ID: 1437

UniProt: P04141

Pathways: JAK-STAT Signalweg, Cellular Response to Molecule of Bacterial Origin