CDKN1C Antikörper (pThr310)

Produktnummer ABIN703045

Produktdetails anti-CDKN1C Antikörper

Target: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Bindungsspezifität: pThr310

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDKN1C Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This phosphorylation site is homologous to that of Thr342 in Mouse.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human p57 Kip2 around the phosphorylation site of Thr310 [EQ(p-T)PR]

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CDKN1C

Target: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Andere Bezeichnung: p57 Kip2 (CDKN1C Produkte)

Synonyme: BWCR antikoerper, BWS antikoerper, KIP2 antikoerper, WBS antikoerper, p57 antikoerper, p57Kip2 antikoerper, cb961 antikoerper, p27Xic1-a antikoerper, zgc:86618 antikoerper, AL024410 antikoerper, CDKI antikoerper, Kip2 antikoerper, p57(kip2) antikoerper, p57KIP2 antikoerper, cyclin dependent kinase inhibitor 1C antikoerper, cyclin-dependent kinase inhibitor 1Ca antikoerper, cyclin-dependent kinase inhibitor 1C (P57) antikoerper, cyclin-dependent kinase inhibitor 1C antikoerper, CDKN1C antikoerper, cdkn1ca antikoerper, Cdkn1c antikoerper

Hintergrund:

Synonyms: BWS, WBS, p57, BWCR, KIP2, p57Kip2, Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, CDKN1C

Background: Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.

Gen-ID: 1028

UniProt: P49918

Pathways: Zellzyklus, Dopaminergic Neurogenesis