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HSPB8 Antikörper (AA 101-196)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HSPB8 in WB, ELISA, IF (p), IF (cc), IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human und Maus.
Produktnummer ABIN702445

Kurzübersicht für HSPB8 Antikörper (AA 101-196) (ABIN702445)

Target

Alle HSPB8 Antikörper anzeigen
HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Reaktivität

  • 92
  • 37
  • 26
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 76
  • 19
  • 1
Kaninchen

Klonalität

  • 71
  • 25
Polyklonal

Konjugat

  • 49
  • 7
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HSPB8 Antikörper ist unkonjugiert

Applikation

  • 74
  • 41
  • 31
  • 26
  • 21
  • 19
  • 12
  • 12
  • 7
  • 7
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 22
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 101-196

    Kreuzreaktivität

    Human, Maus

    Homologie

    Rat,Dog,Cow,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human HSP22

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

    Andere Bezeichnung

    Hsp22

    Hintergrund

    Synonyms: CMT2L, CRYAC, DHMN 2, DHMN2, E2 induced gene 1 protein, E2IG1, H11, Heat shock 22 kDa protein 8, Heat shock protein 22, Heat shock protein beta 8, Hereditary motor neuropathy distal, HMN 2, HMN2, HSB8, HSPB 8, HSPB8, Protein kinase H11, Small stress protein like protein HSP22, Spinal muscular atrophy distal adult autosomal dominant, Alpha crystallin C chain, Charcot Marie Tooth disease axonal type 2L, Charcot Marie Tooth disease spinal.

    Background: Hsp22 (HSPB8) is a 196-amino acid protein that contains a central portion homologous to a highly conserved HSP-alpha crystallin domain common to all the small heat shock protein (HSP20) family members. Hsp22 is a monomeric protein which interacts with HSPB1. It displays temperature-dependent chaperone activity. The highest abundance of Hsp22 is in skeletal muscle, heart, and placenta. Mutations in the HSPB8 gene are associated with the inherited peripheral neuropathies, autosomal dominant distal hereditary motor neuropathy type IIA (dSMA) and axonal Charcot-Marie-Tooth disease type 2L (CMT2L).

    Gen-ID

    26353
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