VCAM1 Antikörper

Produktnummer ABIN7014002

Der Ratte Monoklonal anti-VCAM1 Antikörper (Klon 429 (MVCAM-A)) (ABIN7014002) detektiert spezifisch VCAM1 in FACS, IP, IHC (fro) und Func. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für VCAM1 Antikörper (ABIN7014002)

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser VCAM1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Klon: 429 (MVCAM-A)

Produktdetails anti-VCAM1 Antikörper

Verwendungszweck: Anti-Ms CD106 Purified Azide Free

Spezifität: The rat monoclonal antibody 429 (also known as MVCAM.A) recognizes an extracellular epitope of murine CD106, a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule.

Aufreinigung: Purified by protein-G affinity chromatography.

Immunogen: Murine preadipose cell line PA6

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-4 μg/mL.
Functional application: Blocking

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Konservierungsmittel: Azide free

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu VCAM1

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Andere Bezeichnung: CD106

Hintergrund: Vascular cell adhesion molecule 1,CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity.,Vcam-1

Gen-ID: 22329

UniProt: Q3UPN1

Pathways: Carbohydrate Homeostasis