SIRPA Antikörper

Produktnummer ABIN7013993

Der Maus Monoklonal anti-SIRPA Antikörper (Klon 15-414) (ABIN7013993) detektiert spezifisch SIRPA in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SIRPA Antikörper (ABIN7013993)

Target: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SIRPA Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 15-414

Produktdetails anti-SIRPA Antikörper

Verwendungszweck: Anti-Hu CD172a Purified

Produktmerkmale: The mouse monoclonal antibody 15-414 recognizes en extracellular epitope of CD172a (SIRP alpha), an approximately 90 kDa transmembrane glycoprotein expressed on cells of myeloid origin and neurons.

Aufreinigung: Purified by protein-A affinity chromatography.

Immunogen: Kg-1a cell line

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu SIRPA

Target: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Andere Bezeichnung: CD172a

Hintergrund: Signal regulatory protein alpha,CD172a, the signal-regulatory protein alpha (SIRP alpha), also known as SH2 domain-containing phosphatase substrate-1 (SHPS1), is a 75-110 kDa transmembrane glycoprotein expressed mainly on granulocytes, monocytes, macrophages, dendritic cells and neurons. Its extracellular ligand is CD47. CD172a serves as a substrate of activated receptor tyrosine kinases and upon phosphorylation it recruits SH2 domain-containing tyrosine phosphatases, thereby regulating signal transduction processes related to cell activation, transmigration and phagocytosis. CD172a is a specific marker of cardiomyocytes derived from human pluripotent stem cells and serves as a negative regulator of signaling and growth in myeloid progenitor cells.,PTPNS1, BIT, MFR, SIRPA, SHPS1

Gen-ID: 140885

UniProt: P78324