SIRPA Antikörper
Kurzübersicht für SIRPA Antikörper (ABIN7013993)
Target
Alle SIRPA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Hu CD172a Purified
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Spezifität
- The mouse monoclonal antibody 15-414 recognizes en extracellular epitope of CD172a (SIRP alpha), an approximately 90 kDa transmembrane glycoprotein expressed on cells of myeloid origin and neurons.
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Immunogen
- Kg-1a cell line
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Isotyp
- IgG2a
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anti-Signal-Regulatory Protein alpha (SIRPA) (AA 235-373) antibody
SIRPA Reaktivität: Human FACS, ELISA Wirt: Maus Monoclonal 2H7E2 unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 28-507) antibodySIRPA Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 4C7 unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 395-504) antibodySIRPA Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 105-324) antibodySIRPA Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 56-296) antibodySIRPA Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) antibodySIRPA Reaktivität: Human WB, IF Wirt: Kaninchen Monoclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (C-Term) antibodySIRPA Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (Internal Region) antibodySIRPA Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 31-373) antibodySIRPA Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) antibody (FITC)SIRPA Reaktivität: Human FACS Wirt: Maus Monoclonal 15-414 FITC
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Applikationshinweise
- Flow cytometry: Recommended dilution: 1-4 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- SIRPA (Signal-Regulatory Protein alpha (SIRPA))
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Andere Bezeichnung
- CD172a
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Hintergrund
- Signal regulatory protein alpha,CD172a, the signal-regulatory protein alpha (SIRP alpha), also known as SH2 domain-containing phosphatase substrate-1 (SHPS1), is a 75-110 kDa transmembrane glycoprotein expressed mainly on granulocytes, monocytes, macrophages, dendritic cells and neurons. Its extracellular ligand is CD47. CD172a serves as a substrate of activated receptor tyrosine kinases and upon phosphorylation it recruits SH2 domain-containing tyrosine phosphatases, thereby regulating signal transduction processes related to cell activation, transmigration and phagocytosis. CD172a is a specific marker of cardiomyocytes derived from human pluripotent stem cells and serves as a negative regulator of signaling and growth in myeloid progenitor cells.,PTPNS1, BIT, MFR, SIRPA, SHPS1
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Gen-ID
- 140885
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UniProt
- P78324
Target
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