CD2 Antikörper (PE)

Produktnummer ABIN7013991

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch CD2 in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für CD2 Antikörper (PE) (ABIN7013991)

Target: CD2

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD2 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: RM2-5

Produktdetails anti-CD2 Antikörper (PE)

Verwendungszweck: Anti-Ms CD2 PE

Spezifität: The rat monoclonal antibody RM2-5 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.

Aufreinigung: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: murine thymocytes

Isotyp: IgG2b lambda

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu CD2

Target: CD2

Andere Bezeichnung: CD2

Hintergrund: CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,LFA-2, Ly37, Ly-37

Gen-ID: 12481

UniProt: P08920