CD2 Antikörper
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- Target Alle CD2 Antikörper anzeigen
- CD2
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD2 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
- Spezifität
- The rat monoclonal antibody RM2-5 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.
- Aufreinigung
- Purified by protein-G affinity chromatography.
- Endotoxin-Niveau
- Low Endotoxin
- Immunogen
- murine thymocytes
- Klon
- RM2-5
- Isotyp
- IgG2b lambda
- Top Product
- Discover our top product CD2 Primärantikörper
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- Applikationshinweise
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Functional application: Blocking.
Flow cytometry: Recommended dilution: 1-4 μg/mL - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- Target
- CD2
- Andere Bezeichnung
- CD2 (CD2 Produkte)
- Synonyme
- CD2 antikoerper, LFA-2 antikoerper, Ly-37 antikoerper, Ly37 antikoerper, SRBC antikoerper, T11 antikoerper, CD2R antikoerper, LFA2 antikoerper, OX-34 antikoerper, OX34 antikoerper, CD2 molecule antikoerper, CD2 antigen antikoerper, Cd2 molecule antikoerper, CD2 antikoerper, Cd2 antikoerper
- Hintergrund
- CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,LFA-2, Ly37, Ly-37
- Gen-ID
- 12481
- UniProt
- P08920
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