CD2 Antikörper

Produktnummer ABIN7013989

Der Ratte Monoklonal Anti-CD2-Antikörper wurde für FACS, IP und Func validiert. Er ist geeignet, CD2 in Proben von Maus zu detektieren.

Kurzübersicht für CD2 Antikörper (ABIN7013989)

Target: CD2

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Klon: RM2-5

Produktdetails anti-CD2 Antikörper

Verwendungszweck: Anti-Ms CD2 Purified Low Endotoxin

Spezifität: The rat monoclonal antibody RM2-5 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.

Aufreinigung: Purified by protein-G affinity chromatography.

Endotoxin-Niveau: Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

Immunogen: murine thymocytes

Isotyp: IgG2b lambda

Anwendungsinformationen

Applikationshinweise: Functional application: Blocking.
Flow cytometry: Recommended dilution: 1-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu CD2

Target: CD2

Andere Bezeichnung: CD2

Hintergrund: CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,LFA-2, Ly37, Ly-37

Gen-ID: 12481

UniProt: P08920