HDAC6 Antikörper
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- Target Alle HDAC6 Antikörper anzeigen
- HDAC6 (Histone Deacetylase 6 (HDAC6))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser HDAC6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Verwendungszweck
- Anti-HDAC6 Purified
- Spezifität
- The mouse monoclonal antibody 159 recognizes SE domain of human histone deacetylase 6 (HDAC6, an intracellular antigen), amino acids 971-981.
- Keine Kreuzreaktivität
- Maus, Zebrafisch (Danio rerio)
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Immunogen
- human HDAC6
- Klon
- 159
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product HDAC6 Primärantikörper
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- Applikationshinweise
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Western blotting: Recommended dilution: 1-5 μg/mL.
Immunocytochemistry: Recommended dilution: 5-10 μg/mL. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- Target
- HDAC6 (Histone Deacetylase 6 (HDAC6))
- Andere Bezeichnung
- HDAC6 (HDAC6 Produkte)
- Hintergrund
- Histone deacetylase 6,Histone deacetylase 6 (HDAC6), like other histone deacetylases, affects gene expression by regulation of chromatin remodeling. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. Besides histones, HDAC6 deacetylates also other substrates including alpha tubulin and HSP90 alpha, and is involved in protein trafficking and degradation, as well as in affecting of cell shape and migration. Deregulation of HDAC6 expression and activity is associated with many diseases.,Histone deacetylase 6
- Gen-ID
- 10013
- UniProt
- Q9NSW6
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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