HDAC6 Antikörper
Kurzübersicht für HDAC6 Antikörper (ABIN7013926)
Target
Alle HDAC6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-HDAC6 Purified
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Keine Kreuzreaktivität
- Maus, Zebrafisch (Danio rerio)
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Produktmerkmale
- The mouse monoclonal antibody 236 recognizes D1 domain of human histone deacetylase 6 (HDAC6, intracellular antigen), amino acids 71-91.
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Immunogen
- human HDAC6
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Isotyp
- IgG2b, kappa
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Applikationshinweise
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Western blotting: Recommended dilution: 1-5 μg/mL.
Immunocytochemistry: Recommended dilution: 5-10 μg/mL.
Flow cytometry: Recommended dilution: 0.5-4 μg/mL. Intracellular staining. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- HDAC6 (Histone Deacetylase 6 (HDAC6))
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Andere Bezeichnung
- HDAC6
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Hintergrund
- Histone deacetylase 6,Histone deacetylase 6 (HDAC6), like other histone deacetylases, affects gene expression by regulation of chromatin remodeling. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. Besides histones, HDAC6 deacetylates also other substrates including alpha tubulin and HSP90 alpha, and is involved in protein trafficking and degradation, as well as in affecting of cell shape and migration. Deregulation of HDAC6 expression and activity is associated with many diseases.,Histone deacetylase 6
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Gen-ID
- 10013
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UniProt
- Q9NSW6
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Target
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