HDAC6 Antikörper

Produktnummer ABIN7013923

Der Maus Monoklonal Anti-HDAC6-Antikörper wurde für WB, ELISA und ICC validiert. Er ist geeignet, HDAC6 in Proben von Human zu detektieren.

Kurzübersicht für HDAC6 Antikörper (ABIN7013923)

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HDAC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Klon: 3D2

Produktdetails anti-HDAC6 Antikörper

Verwendungszweck: Anti-HDAC6 Purified

Spezifität: The mouse monoclonal antibody 3D2 recognizes D2 domain of human histone deacetylase 6 (HDAC6, intracellular antigen), amino acids 471-481.

Keine Kreuzreaktivität: Maus, Zebrafisch (Danio rerio)

Aufreinigung: Purified by protein-A affinity chromatography.

Immunogen: human HDAC6

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Western blotting: Recommended dilution: 1-5 μg/mL.
Immunocytochemistry: Recommended dilution: 5-10 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu HDAC6

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Andere Bezeichnung: HDAC6

Hintergrund: Histone deacetylase 6,Histone deacetylase 6 (HDAC6), like other histone deacetylases, affects gene expression by regulation of chromatin remodeling. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. Besides histones, HDAC6 deacetylates also other substrates including alpha tubulin and HSP90 alpha, and is involved in protein trafficking and degradation, as well as in affecting of cell shape and migration. Deregulation of HDAC6 expression and activity is associated with many diseases.,Histone deacetylase 6

Gen-ID: 10013

UniProt: Q9NSW6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling