YAP1 Antikörper (pSer127)
Kurzübersicht für YAP1 Antikörper (pSer127) (ABIN7265224)
Target
Alle YAP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer127
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Produktmerkmale
- Phosphorylated antibody
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Aufreinigung
- Affinity purification
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Immunogen
- A synthetic phosphorylated peptide around S127 of human YAP1 (NP_001123617.1).
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:1000 IF 1:20-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- YAP1 (Yes-Associated Protein 1 (YAP1))
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Andere Bezeichnung
- YAP1
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Hintergrund
- This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Molekulargewicht
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Observed_MW: 60 kDa/68 kDa
Calculated_MW: 36 kDa/48 kDa/49 kDa/50 kDa/52 kDa/53 kDa/54 kDa
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Gen-ID
- 10413
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UniProt
- P46937
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Pathways
- MAPK Signalweg, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
Target
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