CDK6 Antikörper (pTyr13)

Produktnummer ABIN7265168

Dieses Anti-CDK6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CDK6 in WB. Geeignet für Human und Maus.

Kurzübersicht für CDK6 Antikörper (pTyr13) (ABIN7265168)

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CDK6 Antikörper

Bindungsspezifität: pTyr13

Produktmerkmale: Phosphorylated antibody

Aufreinigung: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding Y13 of human CDK6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CDK6

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Andere Bezeichnung: CDK6

Hintergrund: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Molekulargewicht:

Observed_MW: 37 kDa

Calculated_MW: 36 kDa

Gen-ID: 1021

UniProt: Q00534

Pathways: Zellzyklus, Mitotic G1-G1/S Phases