CKAP5 Antikörper

Produktnummer ABIN7264583

Dieses Anti-CKAP5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CKAP5 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für CKAP5 Antikörper (ABIN7264583)

Target: CKAP5 (Cytoskeleton Associated Protein 5 (CKAP5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CKAP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CKAP5 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human CKAP5 (NP_001008938.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CKAP5

Target: CKAP5 (Cytoskeleton Associated Protein 5 (CKAP5))

Andere Bezeichnung: CKAP5

Hintergrund: This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation, it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molekulargewicht:

Observed_MW: 250 kDa

Calculated_MW: 218 kDa/225 kDa/226 kDa

Gen-ID: 9793

UniProt: Q14008

Pathways: M Phase