NEDD4-2 Antikörper
Kurzübersicht für NEDD4-2 Antikörper (ABIN7264127)
Target
Alle NEDD4-2 (NEDD4L) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein of human NEDD4L (NP_056092.2).
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Isotyp
- IgG
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anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 836-955) antibody
NEDD4L Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 1-100) antibodyNEDD4L Reaktivität: Human ELISA, WB, IP Wirt: Maus Monoclonal 1D2 unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 289-494) antibodyNEDD4L Reaktivität: Human ELISA, WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) antibodyNEDD4L Reaktivität: Human, Maus ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (pSer448) antibodyNEDD4L Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (Middle Region) antibodyNEDD4L Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 1-100) antibodyNEDD4L Reaktivität: Human ELISA, WB Wirt: Maus Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 275-325) antibodyNEDD4L Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein WB, IHC, IF, IP, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 225-275) antibodyNEDD4L Reaktivität: Human, Maus, Rind (Kuh), Schwein, Kaninchen WB, IHC, IF, IP, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) (AA 1-911) antibodyNEDD4L Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
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Applikationshinweise
- IHC 1:50-1:200 IF 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- NEDD4-2 (NEDD4L) (E3 ubiquitin-protein ligase NEDD4-like (NEDD4L))
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Andere Bezeichnung
- NEDD4L
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Hintergrund
- This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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Gen-ID
- 23327
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UniProt
- Q96PU5
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Pathways
- Negative Regulation of Transporter Activity
Target
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