FLT3 Antikörper
Kurzübersicht für FLT3 Antikörper (ABIN7012052)
Target
Alle FLT3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein of human FLT3
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Isotyp
- IgG
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anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody
FLT3 Reaktivität: Human ELISA, IHC Wirt: Maus Monoclonal 7B7C3 unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 62-295) antibodyFLT3 Reaktivität: Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 334-543) antibodyFLT3 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 335-544) antibodyFLT3 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64), (N-Term) antibodyFLT3 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB01544 unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64) antibodyFLT3 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (FITC)FLT3 Reaktivität: Human FACS Wirt: Maus Monoclonal BV10A4 FITC
anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (PE)FLT3 Reaktivität: Human FACS Wirt: Maus Monoclonal BV10A4 PE
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 650-750) antibodyFLT3 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (C-Term) antibodyFLT3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
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Andere Bezeichnung
- FLT3
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Hintergrund
- This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
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Molekulargewicht
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Observed_MW: 113 kDa
Calculated_MW: 108 kDa/112 kDa
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Gen-ID
- 2322
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UniProt
- P36888
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Pathways
- RTK Signalweg
Target
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