PDHB Antikörper

Produktnummer ABIN7262853

Dieses Anti-PDHB-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PDHB in WB. Geeignet für Human, Ratte und Maus.

Kurzübersicht für PDHB Antikörper (ABIN7262853)

Target: PDHB (Pyruvate Dehydrogenase beta (PDHB))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDHB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PDHB Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human PDHB (NP_000916.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PDHB

Target: PDHB (Pyruvate Dehydrogenase beta (PDHB))

Andere Bezeichnung: PDHB

Hintergrund: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene.

Molekulargewicht:

Observed_MW: 39 kDa

Calculated_MW: 37 kDa/39 kDa

Gen-ID: 5162

UniProt: P11177

Pathways: Warburg Effekt