TPT1 Antikörper (AA 85-172)

Produktnummer ABIN701080

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TPT1 in WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human und Maus. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für TPT1 Antikörper (AA 85-172) (ABIN701080)

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-TPT1 Antikörper

Bindungsspezifität: AA 85-172

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TCTP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-TPT1 Antikörper (ABIN701080)

Wu, Guo, Min, Zhou, Li, Li, Luo: "Upregulation of TCTP expression in human skin squamous cell carcinoma increases tumor cell viability through anti-apoptotic action of the protein." in: Experimental and therapeutic medicine, Vol. 3, Issue 3, pp. 437-442, (2012) (PubMed).

Details zu TPT1

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Andere Bezeichnung: TCTP

Hintergrund:

Synonyms: FLJ27337, Fortilin, Histamine releasing factor, Histamine-releasing factor, HRF, Immunoglobulin E-dependent, p02, p23, TCTP, TCTP_HUMAN, TPT1, Translationally controlled tumor protein, Translationally-controlled tumor protein, Tumor protein translationally controlled 1, tumor protein translationally-controlled 1, tumor protein, translationally-controlled 1.

Background: TCTP is involved in calcium binding and microtubule stabilization. It is an immunoglobulin E dependent histamine-releasing factor produced by lymphocytes of atopic children and present in biologic fluids of allergic patients. Both human and mouse recombinant HRF proteins caused histamine release from human basophils of a subpopulation of donors (referenced from OMIM).

Gen-ID: 7178

Pathways: Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling