RGS4 Antikörper

Produktnummer ABIN7259747

Dieses Anti-RGS4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RGS4 in WB und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für RGS4 Antikörper (ABIN7259747)

Target: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-RGS4 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human RGS4 (NP_005604.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RGS4

Target: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Andere Bezeichnung: RGS4

Hintergrund: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene.

Molekulargewicht:

Observed_MW: 30 kDa

Calculated_MW: 10 kDa/21 kDa/23 kDa/33 kDa

Gen-ID: 5999

UniProt: P49798

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling