HCK Antikörper

Produktnummer ABIN7257940

Dieses Anti-HCK-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HCK in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für HCK Antikörper (ABIN7257940)

Target: HCK (Hemopoietic Cell Kinase (HCK))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HCK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HCK Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human HCK (NP_001165600.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HCK

Target: HCK (Hemopoietic Cell Kinase (HCK))

Andere Bezeichnung: HCK

Hintergrund: The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.

Molekulargewicht:

Observed_MW: 55-60 kDa

Calculated_MW: 57 kDa/59 kDa

Gen-ID: 3055

UniProt: P08631

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling