MKL1 Antikörper
Kurzübersicht für MKL1 Antikörper (ABIN7257724)
Target
Alle MKL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein of human MKL1 (NP_065882.1).
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000 IF 1:50-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))
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Andere Bezeichnung
- MKL1
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Hintergrund
- The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.
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Molekulargewicht
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Observed_MW: 150 kDa
Calculated_MW: 98 kDa
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Gen-ID
- 57591
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UniProt
- Q969V6
Target
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