MICA Antikörper
Kurzübersicht für MICA Antikörper (ABIN7257459)
Target
Alle MICA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Polyclonal Antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein of human MICA (NP_000238.1).
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Isotyp
- IgG
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anti-MHC Class I Polypeptide-Related Sequence A (MICA) (AA 68-97) antibody
MICA Reaktivität: Human WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal RB21777 unconjugated
anti-MHC Class I Polypeptide-Related Sequence A (MICA) antibodyMICA Reaktivität: Human WB, FACS, IP Wirt: Maus Monoclonal MEM-147 unconjugated
anti-MHC Class I Polypeptide-Related Sequence A (MICA) antibodyMICA Reaktivität: Human, Rind (Kuh), Cat, Non-Human Primate ELISA, FACS, IP, ICC, IHC (fro), Func, MS Wirt: Maus Monoclonal W6-32 unconjugated
anti-MHC Class I Polypeptide-Related Sequence A (MICA) antibodyMICA Reaktivität: Human, Rind (Kuh), Cat, Non-Human Primate ELISA, FACS, IP, ICC, IHC (fro), MS Wirt: Maus Monoclonal W6-32 unconjugated
anti-MHC Class I Polypeptide-Related Sequence A (MICA) (AA 120-170) antibodyMICA Reaktivität: Human WB, IHC (p), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-MHC Class I Polypeptide-Related Sequence A (MICA) antibody (Biotin)MICA Reaktivität: Human, Rind (Kuh), Cat, Non-Human Primate ELISA, FACS, IP, ICC, IHC (fro) Wirt: Maus Monoclonal W6-32 Biotin
anti-MHC Class I Polypeptide-Related Sequence A (MICA) antibody (FITC)MICA Reaktivität: Human, Rind (Kuh), Cat, Non-Human Primate FACS Wirt: Maus Monoclonal W6-32 FITC
anti-MHC Class I Polypeptide-Related Sequence A (MICA) antibody (PE)MICA Reaktivität: Human, Rind (Kuh), Cat, Non-Human Primate FACS Wirt: Maus Monoclonal W6-32 PE
anti-MHC Class I Polypeptide-Related Sequence A (MICA) (AA 1-200) antibodyMICA Reaktivität: Human WB, IHC (f) Wirt: Maus Monoclonal unconjugated
anti-MHC Class I Polypeptide-Related Sequence A (MICA) antibody (PE)MICA Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-147 PE
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Applikationshinweise
- WB 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
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Andere Bezeichnung
- MICA
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Hintergrund
- This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.
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Molekulargewicht
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Observed_MW: 43 kDa
Calculated_MW: 31 kDa/42 kDa
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Gen-ID
- 100507436
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UniProt
- Q29983
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Pathways
- Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
Target
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