DUSP12 Antikörper

Produktnummer ABIN7256746

Dieses Anti-DUSP12-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DUSP12 in WB. Geeignet für Human und Maus.

Kurzübersicht für DUSP12 Antikörper (ABIN7256746)

Target: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DUSP12 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human DUSP12 (NP_009171.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DUSP12

Target: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Andere Bezeichnung: DUSP12

Hintergrund: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.

Molekulargewicht:

Observed_MW: 36 kDa

Calculated_MW: 37 kDa

Gen-ID: 11266

UniProt: Q9UNI6

Pathways: Regulation of Carbohydrate Metabolic Process