DUSP12 Antikörper (AA 1-50)

Produktnummer ABIN7452603

Produktdetails anti-DUSP12 Antikörper

Target: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Bindungsspezifität: AA 1-50

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-DUSP12 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 1 and 50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 20 μL/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu DUSP12

Target: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Andere Bezeichnung: DUSP12 (DUSP12 Produkte)

Synonyme: DUSP12 antikoerper, dusp12 antikoerper, zgc:114069 antikoerper, MGC154526 antikoerper, DUSP1 antikoerper, YVH1 antikoerper, 1190004O14Rik antikoerper, AA027408 antikoerper, AW049275 antikoerper, ESTM36 antikoerper, LMW-DSP4 antikoerper, T-DSP4 antikoerper, VH1 antikoerper, mVH1 antikoerper, GKAP antikoerper, dual specificity phosphatase 12 antikoerper, dual specificity phosphatase 12 L homeolog antikoerper, Dual specificity protein phosphatase 12 antikoerper, dual specificity protein phosphatase 12 antikoerper, DUSP12 antikoerper, dusp12 antikoerper, dusp12.L antikoerper, GL50803_36315 antikoerper, MGYG_01770 antikoerper, Dusp12 antikoerper

Hintergrund: Background: Dual specificity protein phosphatase 12 (DUSP12) is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP12 is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain [taken from NCBI Entrez Gene (Gene ID: 11266)].

Gen-ID: 11266

UniProt: Q9UNI6

Pathways: Regulation of Carbohydrate Metabolic Process