UNC13D Antikörper

Produktnummer ABIN7256664

Dieser Anti-UNC13D Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von UNC13D in WB. Geeignet für Human und Maus.

Kurzübersicht für UNC13D Antikörper (ABIN7256664)

Target: UNC13D (Unc-13 Homolog D (UNC13D))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNC13D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-UNC13D Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human UNC13D (NP_954712.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu UNC13D

Target: UNC13D (Unc-13 Homolog D (UNC13D))

Andere Bezeichnung: UNC13D

Hintergrund: This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

Molekulargewicht:

Observed_MW: 123 kDa

Calculated_MW: 41 kDa/123 kDa/128 kDa

Gen-ID: 201294

UniProt: Q70J99

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process