CD3 epsilon Antikörper
Kurzübersicht für CD3 epsilon Antikörper (ABIN7256106)
Target
Alle CD3 epsilon (CD3E) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Produktmerkmale
- Polyclonal Antibody
-
Aufreinigung
- Affinity purification
-
Immunogen
- A synthetic peptide of human CD3E Antigen (NP_000724.1).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- CD3 epsilon (CD3E)
-
Andere Bezeichnung
- CD3E Antigen
-
Hintergrund
- The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
-
Molekulargewicht
-
Observed_MW: 23-25 kDa
Calculated_MW: 23 kDa
-
Gen-ID
- 916
-
UniProt
- P07766
-
Pathways
- T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
Target
-