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TLR3 Antikörper

TLR3 Reaktivität: Human, Maus, Ratte IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7255782
  • Target Alle TLR3 Antikörper anzeigen
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Reaktivität
    • 98
    • 67
    • 30
    • 6
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 85
    • 31
    • 5
    • 2
    Kaninchen
    Klonalität
    • 88
    • 35
    Polyklonal
    Konjugat
    • 53
    • 18
    • 15
    • 9
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TLR3 Antikörper ist unkonjugiert
    Applikation
    • 85
    • 45
    • 38
    • 35
    • 23
    • 18
    • 16
    • 15
    • 13
    • 13
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human TLR3 (NP_003256.1).
    Isotyp
    IgG
    Top Product
    Discover our top product TLR3 Primärantikörper
  • Applikationshinweise
    IF 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Andere Bezeichnung
    TLR3 (TLR3 Produkte)
    Synonyme
    CD283 antikoerper, IIAE2 antikoerper, AI957183 antikoerper, zgc:123006 antikoerper, toll like receptor 3 antikoerper, toll-like receptor 3 antikoerper, TLR3 antikoerper, Tlr3 antikoerper, tlr3 antikoerper
    Hintergrund
    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene.
    Gen-ID
    7098
    UniProt
    O15455
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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