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WISP2 Antikörper

Der Kaninchen Polyklonal Anti-WISP2-Antikörper wurde für IHC und ELISA validiert. Er ist geeignet, WISP2 in Proben von Human zu detektieren.
Produktnummer ABIN7254661

Kurzübersicht für WISP2 Antikörper (ABIN7254661)

Target

Alle WISP2 Antikörper anzeigen
WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

Reaktivität

  • 45
  • 8
  • 6
  • 1
  • 1
  • 1
Human

Wirt

  • 42
  • 8
Kaninchen

Klonalität

  • 43
  • 7
Polyklonal

Konjugat

  • 32
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser WISP2 Antikörper ist unkonjugiert

Applikation

  • 39
  • 17
  • 17
  • 12
  • 11
  • 2
  • 2
  • 2
  • 2
  • 1
Immunohistochemistry (IHC), ELISA
  • Produktmerkmale

    Polyclonal Antibody

    Aufreinigung

    Antigen affinity purification

    Immunogen

    Synthetic peptide of human WISP2

    Isotyp

    IgG
  • Applikationshinweise

    IHC 1:30-1:150, ELISA 1:5000-1:10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.8 mg/mL

    Buffer

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

    Andere Bezeichnung

    WISP2

    Hintergrund

    This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72 % identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.

    UniProt

    O76076

    Pathways

    WNT Signalweg, Growth Factor Binding
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