FBXO32 Antikörper

Produktnummer ABIN7251817

Dieses Anti-FBXO32-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FBXO32 in WB, ELISA und IHC. Geeignet für Human, Ratte und Maus.

Kurzübersicht für FBXO32 Antikörper (ABIN7251817)

Target: FBXO32 (F-Box Protein 32 (FBXO32))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO32 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-FBXO32 Antikörper

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human FBXO32

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:5000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.02 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FBXO32

Target: FBXO32 (F-Box Protein 32 (FBXO32))

Andere Bezeichnung: FBXO32

Hintergrund: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 42 kDa

UniProt: Q969P5