HDAC6 Antikörper (pSer22)
Kurzübersicht für HDAC6 Antikörper (pSer22) (ABIN7250821)
Target
Alle HDAC6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer22
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Produktmerkmale
- Phosphorylated antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Synthesized peptide derived from human HDAC6 around the phosphorylation site of Ser22
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- HDAC6 (Histone Deacetylase 6 (HDAC6))
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Andere Bezeichnung
- HDAC6
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Hintergrund
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
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Molekulargewicht
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Observed_MW: 131 kDa
Calculated_MW: 131 kDa
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UniProt
- Q9UBN7
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Target
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