Filamin A Antikörper (pSer2152)
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- Target Alle Filamin A (FLNA) Antikörper anzeigen
- Filamin A (FLNA) (Filamin A, alpha (FLNA))
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Bindungsspezifität
- pSer2152
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Reaktivität
- Human, Maus, Ratte, Affe
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Filamin A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Produktmerkmale
- Phosphorylated antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Synthesized peptide derived from human Filamin 1 around the phosphorylation site of Ser2152
- Isotyp
- IgG
- Top Product
- Discover our top product FLNA Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Filamin A (FLNA) (Filamin A, alpha (FLNA))
- Andere Bezeichnung
- FLNA (FLNA Produkte)
- Hintergrund
- The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
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Observed_MW: 280 kDa
Calculated_MW: 281 kDa
- UniProt
- P21333
- Pathways
- T-Zell Rezeptor Signalweg, Maintenance of Protein Location
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