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Filamin A Antikörper (pSer2152)

FLNA Reaktivität: Human, Maus, Ratte, Affe WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7250800
  • Target Alle Filamin A (FLNA) Antikörper anzeigen
    Filamin A (FLNA) (Filamin A, alpha (FLNA))
    Bindungsspezifität
    • 15
    • 15
    • 12
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer2152
    Reaktivität
    • 103
    • 32
    • 20
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Affe
    Wirt
    • 95
    • 7
    • 1
    Kaninchen
    Klonalität
    • 86
    • 17
    Polyklonal
    Konjugat
    • 44
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser Filamin A Antikörper ist unkonjugiert
    Applikation
    • 52
    • 31
    • 28
    • 28
    • 27
    • 23
    • 13
    • 10
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Produktmerkmale
    Phosphorylated antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Synthesized peptide derived from human Filamin 1 around the phosphorylation site of Ser2152
    Isotyp
    IgG
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  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Filamin A (FLNA) (Filamin A, alpha (FLNA))
    Andere Bezeichnung
    FLNA (FLNA Produkte)
    Hintergrund
    The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht

    Observed_MW: 280 kDa

    Calculated_MW: 281 kDa

    UniProt
    P21333
    Pathways
    T-Zell Rezeptor Signalweg, Maintenance of Protein Location
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