FGFR4 Antikörper (pTyr642)
-
- Target Alle FGFR4 Antikörper anzeigen
- FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
-
Bindungsspezifität
- pTyr642
-
Reaktivität
- Human, Ratte, Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser FGFR4 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA
- Produktmerkmale
- Phosphorylated antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Synthesized peptide derived from human FGFR-4 around the phosphorylation site of Tyr642
- Isotyp
- IgG
- Top Product
- Discover our top product FGFR4 Primärantikörper
-
-
- Applikationshinweise
- WB 1:500-1:2000, ELISA 1:10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
- Andere Bezeichnung
- FGFR4 (FGFR4 Produkte)
- Hintergrund
- The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. FGFR4 (Fibroblast Growth Factor Receptor 4) is a Protein Coding gene. Diseases associated with FGFR4 include Prostate Cancer and Neuroma. Among its related pathways are GPCR Pathway and RET signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is FGFR3.
- Molekulargewicht
-
Observed_MW: 90 kDa
Calculated_MW: 88 kDa
- UniProt
- P22455
- Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding
-