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FGFR4 Antikörper (pTyr642)

Der Kaninchen Polyklonal Anti-FGFR4-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, FGFR4 in Proben von Human, Ratte und Maus zu detektieren.
Produktnummer ABIN7250791

Kurzübersicht für FGFR4 Antikörper (pTyr642) (ABIN7250791)

Target

Alle FGFR4 Antikörper anzeigen
FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

Reaktivität

  • 88
  • 36
  • 25
  • 1
  • 1
Human, Ratte, Maus

Wirt

  • 72
  • 18
  • 2
  • 1
Kaninchen

Klonalität

  • 65
  • 25
  • 2
Polyklonal

Konjugat

  • 50
  • 8
  • 7
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FGFR4 Antikörper ist unkonjugiert

Applikation

  • 52
  • 40
  • 24
  • 22
  • 13
  • 13
  • 12
  • 11
  • 7
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 15
    • 11
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr642

    Produktmerkmale

    Phosphorylated antibody

    Aufreinigung

    Affinity purification

    Immunogen

    Synthesized peptide derived from human FGFR-4 around the phosphorylation site of Tyr642

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:500-1:2000, ELISA 1:10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

    Andere Bezeichnung

    FGFR4

    Hintergrund

    The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. FGFR4 (Fibroblast Growth Factor Receptor 4) is a Protein Coding gene. Diseases associated with FGFR4 include Prostate Cancer and Neuroma. Among its related pathways are GPCR Pathway and RET signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is FGFR3.

    Molekulargewicht

    Observed_MW: 90 kDa

    Calculated_MW: 88 kDa

    UniProt

    P22455

    Pathways

    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding
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