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FGFR4 Antikörper (pTyr642)

FGFR4 Reaktivität: Human, Ratte, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7250791
  • Target Alle FGFR4 Antikörper anzeigen
    FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
    Bindungsspezifität
    • 14
    • 11
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr642
    Reaktivität
    • 76
    • 35
    • 23
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 67
    • 9
    • 2
    • 1
    Kaninchen
    Klonalität
    • 60
    • 16
    • 2
    Polyklonal
    Konjugat
    • 43
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FGFR4 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 34
    • 21
    • 20
    • 12
    • 12
    • 12
    • 8
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Produktmerkmale
    Phosphorylated antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Synthesized peptide derived from human FGFR-4 around the phosphorylation site of Tyr642
    Isotyp
    IgG
    Top Product
    Discover our top product FGFR4 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, ELISA 1:10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))
    Andere Bezeichnung
    FGFR4 (FGFR4 Produkte)
    Hintergrund
    The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. FGFR4 (Fibroblast Growth Factor Receptor 4) is a Protein Coding gene. Diseases associated with FGFR4 include Prostate Cancer and Neuroma. Among its related pathways are GPCR Pathway and RET signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is FGFR3.
    Molekulargewicht

    Observed_MW: 90 kDa

    Calculated_MW: 88 kDa

    UniProt
    P22455
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding
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