beta Catenin Antikörper (pTyr654)
Kurzübersicht für beta Catenin Antikörper (pTyr654) (ABIN7250716)
Target
Alle beta Catenin (CATNB) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr654
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Produktmerkmale
- Phosphorylated antibody
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Aufreinigung
- Affinity purification
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Immunogen
- Synthesized peptide derived from human Catenin-beta around the phosphorylation site of Tyr654
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Isotyp
- IgG
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anti-Catenin, beta (CATNB) (pSer33), (pSer37) antibody
CATNB Reaktivität: Human, Maus, Ratte WB, FACS, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 661-781) antibodyCATNB Reaktivität: Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio) WB, FACS, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Catenin, beta (CATNB) (C-Term) antibodyCATNB Reaktivität: Human, Maus, Ratte, Huhn, Rind (Kuh), Hund, Schwein, Kaninchen, Schaf, Affe, Hamster, Avian, Cat, Esel, Ziege, Meerschweinchen, Pferd WB, IF Wirt: Ziege Polyclonal unconjugated
anti-Catenin, beta (CATNB) (C-Term) antibodyCATNB Reaktivität: Human, Zebrafisch (Danio rerio) WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Catenin, beta (CATNB) (pSer33), (pSer37), (pThr41) antibodyCATNB Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 439-675) antibodyCATNB Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Catenin, beta (CATNB) (AA 439-675) antibodyCATNB Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C11 unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB Reaktivität: Human, Maus, Hamster WB, IP, ICC, ICFC Wirt: Maus Monoclonal EM-22 unconjugated
anti-Catenin, beta (CATNB) antibodyCATNB Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Maus Monoclonal 4A3H3 unconjugated
anti-Catenin, beta (CATNB) (AA 764-781) antibodyCATNB Reaktivität: Human, Maus, Ratte WB, IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Andere Bezeichnung
- Catenin beta
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Hintergrund
- Key dowstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes.Involved in the regulation of cell adhesion. The majority of beta-catenin is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.
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Molekulargewicht
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Observed_MW: 75 kDa
Calculated_MW: 85 kDa
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UniProt
- P35222
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Pathways
- Peptide Hormone Metabolism
Target
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