SGK1 Antikörper
Kurzübersicht für SGK1 Antikörper (ABIN7250530)
Target
Alle SGK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Produktmerkmale
- Monoclonal Antibody
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Aufreinigung
- Protein A purification
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Immunogen
- Synthetic Peptide of SGK1
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Isotyp
- IgG
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anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 172-431) antibody
SGK1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 1-431) antibodySGK1 Reaktivität: Human WB, ELISA, IF, IHC (p), RNAi Wirt: Maus Monoclonal 4D7-G3 unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 1-90) antibodySGK1 Reaktivität: Human ELISA, IF, IHC (p) Wirt: Maus Monoclonal 3G8 unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 145-386) antibodySGK1 Reaktivität: Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 247-406) antibodySGK1 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (AA 1-90) antibodySGK1 Reaktivität: Human ELISA, IF, IHC (p) Wirt: Maus Monoclonal 3E3 unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (pSer78) antibodySGK1 Reaktivität: Human WB, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (pSer422) antibodySGK1 Reaktivität: Human WB, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (pThr256) antibodySGK1 Reaktivität: Human WB, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-serum/glucocorticoid Regulated Kinase 1 (SGK1) (pSer78) antibodySGK1 Reaktivität: Human, Maus, Ratte IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- IHC 1:100-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
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Andere Bezeichnung
- SGK1
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Hintergrund
- Protein kinase that plays an important role in cellular stress response. Activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion. Sustained high levels and activity may contribute to conditions such as hypertension and diabetic nephropathy. Mediates cell survival signals, phosphorylates and negatively regulates pro-apoptotic FOXO3A. Phosphorylates NEDD4L, which leads to its inactivation and to the subsequent activation of various channels and transporters such as ENaC, KCNA3/Kv1.3 or EAAT1. Isoform 2 exhibited a greater effect on cell plasma membrane expression of ENaC and Na(+) transport than isoform 1.
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UniProt
- O00141
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Pathways
- MAPK Signalweg, Notch Signalweg, Steroid Hormone Mediated Signaling Pathway
Target
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