HSPB8 Antikörper
Kurzübersicht für HSPB8 Antikörper (ABIN7250452)
Target
Alle HSPB8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Produktmerkmale
- Monoclonal Antibody
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Aufreinigung
- Protein A purification
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Immunogen
- Recombinant Protein
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000-2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
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Andere Bezeichnung
- Crystallin-alpha C
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Hintergrund
- The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
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Molekulargewicht
- 22 kDa
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UniProt
- Q9UJY1
Target
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