Der Maus Monoklonal anti-LC3B Antikörper (Klon 6E4) (ABIN7250326) detektiert spezifisch LC3B in IHC (p).
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
LC3B (MAP1LC3B)
(Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))
Andere Bezeichnung
MAP1LC3B
Hintergrund
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. MAP1LC3B (Microtubule Associated Protein 1 Light Chain 3 Beta) is a Protein Coding gene. Diseases associated with MAP1LC3B include Sporadic Pheochromocytoma and Lacrimal Gland Adenocarcinoma. Among its related pathways are Vesicle-mediated transport and Senescence and Autophagy in Cancer. GO annotations related to this gene include microtubule binding. An important paralog of this gene is MAP1LC3B2.